Arestin® is an antibiotic in dry powder form that is delivered locally into the gum pockets. It is an adjunct to deep cleaning (“scaling and root planing”) in the treatment of gum disease. The active ingredient of Arestin® is minocycline, an antibiotic in the tetracycline family that has a broad spectrum of activity against bacteria living in the gums. Arestin® is coupled to its carrier microspheres that slowly release minocycline to the surrounding area so its function against bacterial growth can be prolonged. It should not be used by nursing mothers nor in individuals who have allergies to minocycline or tetracyclines. Following the administration of Arestin®, patients should avoid eating sticky or crunchy food at the treated area for at least 1 week. Arestin® is sometimes repeated every 3 months up to a total period of 9 months to ensure optimal results.